Nigella Sativa is a medicinal plant commonly used worldwide in various traditional medical systems. Originally from Egypt, also known as black cumin oil. The annual flowering plant belongs to the Ranunculaceae family and is an excellent phytomedicine.
Nigella oil is known for its diuretic, antihypertensive, antidiabetic, anticancer, immunomodulatory, antimicrobial, antihelmintic, analgesic and calming, spasmolytic, bronchodilator, anti-inflammatory, anti-tussive, gastro-protective, hepatoprotective, low-density lipoprotein properties. lowering cholesterol, protective and antioxidant kidney properties.
The world is going through difficult times. It's the race against time to find a vaccine against the new coronavirus (COVID-19) every day becomes more difficult. Many articles with their first research results on the pathophysiology of COVID-19 infection give some clues to invent a cure for this pandemic.
The importance of immunomodulation in the human body. A recent study published in the Journal of Autoimmunity reported that severe cases admitted to the intensive care unit showed elevated levels of pro-inflammatory cytokines, including TNFα (tumor necrosis factor Alpha) which are believed to promote severity of the disease. The variety of symptoms observed in patients infected with COVID-19 shows.
Another study published in The Lancet on the pathological outcomes of COVID-19 associated with acute respiratory distress syndrome reported that lymphopenia was a common feature in patients and suggested that it could be a critical factor associated with severity and to disease mortality.
A letter to the editor published in Nature Medicine reported that an increase in the cell secreting antibodies, producing antibodies to immunoglobulin M and immunoglobulin G that bound to COVID-19 causing the coronavirus SARS-CoV- 2 were detected in the blood before symptoms recovered and the immunological changes persisted for at least 7 days after the symptoms had completely resolved.
Immune modulation is the regulatory adjustment of the immune system. No one knows how long the COVID-19 situation will last. Reports have suggested that one of the three methods that can prevent infection is immune modulation; vaccine and improvement of human behavior, personal hygiene being the others.
Scientists and doctors around the world are fighting. There is a cure for every disease.
Thymoquinone is an abundant component of Nigella seed oil extract. Thymoquinone is known to inhibit inflammation induced by TNF-α. Thymoquinone is known for its lymphoprotective activity and its immune modulation. Another major concern of doctors was the effect on the kidneys and testes.
Thymoquinone is not only a lung protector but also a nephroprotector in diseases caused by inflammation and oxidative stress. Thymoquinone is also known for its protective testicular function.
The Thymoquinone component in Nigella Sativa seed oil is known for its intense immunomodulatory benefits. The anti-inflammatory, antioxidant and immunomodulatory actions of Nigella Sativa have resulted in preventive and bronchodilator effects on obstructive respiratory diseases.
A study published in the Journal of Molecular Biology Reports in 2014 concluded that treating cells with NS extracts before CoV infection decreased replication of the virus.
This is the time when doctors and scientists take note of this natural wonder and try to slow down the COVID-19 pandemic.
Thymoquinone by immunomodulation and its other health benefits can definitely be considered as a medicine intended to prevent or treat the viral infection caused by COVID-19 causing the coronavirus SARS-CoV-2.
Future clinical trials with Thymoquinone will discover how we can use it exactly in the current pandemic state of COVID-19.
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